CARLSBAD, CA--(MARKET WIRE)--Nov 25, 2008 -- Applied Nanoscience Inc. (ANI) (Other OTC:APNN.PK - News), a nanotechnology-based filtration development company, today announced that it received notice of a successful EPA-F.I.F.R.A. registration from its exclusive toll manufacturer of NanoFense, a proprietary antimicrobial nanoparticle formulation developed by ANI to coat or impregnate virtually any air filter media. The completed registration positions Applied Nanoscience to supply their patent-pending silver nanoparticle "coating" to air filtration companies around the world via licensure.

"This positive development with our manufacturing partner moves ANI forward in supplying our proprietary technology to license partners globally while in full compliance in an industry with increasing regulation," said Thomas K. Allen, President and CEO, ANI.

ANI has to date received patents on its platform technology in Russia, Singapore, Taiwan, Australia, New Zealand and India.

F.I.F.R.A. is the Federal Insecticide, Fungicide and Rodenticide Act, a United States federal law with emphasis on protection of the environment and public health.

About ANI

ANI is a marketer and developer of innovative, high performance nanotechnology-based filtration products to customers worldwide and is the owner of NEFT(TM) (Nanoparticle -- Enhanced -- Filtration -- Technology), a broad platform with significant application potential in consumer market segments.

For further information about Applied Nanoscience Inc., please visit: www.appliednanoscience.com

Safe Harbor Statement

This release may contain statements that are forward-looking. Such statements are made based upon current expectations that are subject to risk and uncertainty. ANI does not undertake to update forward-looking statements in this news release to reflect actual results of and changes in assumptions or changes in other factors affecting such forward-looking information. The actual future plans and results of the company could differ significantly from such forward-looking statements.

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