Item 5.02(b) Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers

On November 13, 2009, Kenneth Sprenger's employment as Senior Vice President, Clinical Development and Operations of Neurogen Corporation was terminated without cause. Under Dr. Sprenger's employment agreement, dated as of March 27, 2009, he was entitled to receive, and the Company has paid to him, a severance payment of $375,000 equal to twelve months of his base salary and target bonus.