Item 5.02. Departure of Directors or Certain Officers; Election of Directors;
Appointment of Certain Officers; Compensatory Arrangements of Certain Officers T. Scott Johnson resigned as a director of The Medicines Company (the "Company") effective July 21, 2009. Dr. Johnson resigned from the board of directors to devote his efforts to his new full-time role as Vice President, New Business Ventures & Chief Medical Advisor of the Company. On July23, 2009, the Company issued a press release regarding Dr. Johnson, a copy of which is attached hereto as Exhibit 99.1.
Dr. Johnson had also served as a member of the Company's Audit Committee prior to his commencement of employment with the Company. The Company's board of directors appointed William Crouse, a current member of the board of directors, to fill the vacancy on the Audit Committee created by Dr. Johnson's departure. Item 9.01. Financial Statements and Exhibits
(c) Exhibits
99.1 Press release dated July 23, 2009 entitled "The Medicines Company Appoints T. Scott Johnson as Vice President, New Business Ventures & Chief Medical Advisor"

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