Item 1.01. Entry into a Material Definitive Agreement.

On May 12, 2009, BioMarin Pharmaceutical Inc. (the "Company") amended the Company's Severance Plan and Summary Plan Description (the "Severance Plan") to include the Company's chief executive officer as an eligible participant in the Severance Plan and to amend the Severance Plan to provide that in addition to unvested stock options vesting upon a Change of Control (as defined in the Severance Plan), all restricted stock, restricted stock units and other equity compensation with time-based vesting will also vest upon a Change of Control.

The foregoing description of the Severance Plan is qualified in its entirety by reference to the full text of the Severance Plan, a copy of which will be filed with the Company's Quarterly report on Form 10-Q for the quarter ended June 30, 2009.

Item 5.02. Departure of Directors or Certain Officers; Election of Directors;
Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

The information set forth in Item 1.01 is incorporated by reference in this Item 5.02.

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