ITEM 8.01 OTHER EVENTS.

On October 23, 2008, Simulations Plus, Inc., a California corporation (the "Company" or "us," "our" or "we"), issued a press release announcing a share repurchase program. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

The board of directors has authorized a share repurchase program enabling the buyback of up to $2.5 million of our shares during a 12-month period beginning Monday, October 27, 2008. The Company has opened an account with Citigroup Smith Barney for the purchase of such securities. Funds for any stock purchases will be drawn from the Company's then-current cash reserves.

In implementing a share repurchase program, the Company will comply with the safe harbor provisions contained in Rule 10b-18 under the Securities and Exchange Act of 1934, as amended. Rule 10b-18, as such rule may be amended in the future, shall take precedence over the terms of this program to the extent any conflict should exist or arise in the future.

This report on Form 8-K (the "Report"), including the disclosures set forth herein and exhibits attached hereto, contains certain forward-looking statements that involve substantial risks and uncertainties. When used herein, the terms "anticipates," "expects," "estimates," "believes" and similar expressions, as they relate to us or our management, are intended to identify such forward-looking statements.

Forward-looking statements in this Report or hereafter, including in other publicly available documents filed with the Securities and Exchange Commission (the "Commission"), reports to the stockholders of the Company and other publicly available statements issued or released by us involve known and unknown risks, uncertainties and other factors which could cause our actual results, performance (financial or operating) or achievements to differ from the future results, performance (financial or operating) or achievements expressed or implied by such forward-looking statements. Such future results are based upon management's best estimates based upon current conditions and the most recent results of operations. These risks include, but are not limited to, the risks set forth herein and in such other documents filed with the Commission, each of which could adversely affect our business and the accuracy of the forward-looking statements contained herein. Our actual results, performance or achievements may differ materially from those expressed or implied by such forward-looking statements.